Starting Nplate®

How should I take Nplate®?1

  • Before you receive Nplate® you should first talk with your healthcare provider and understand the benefits and risks of Nplate®.
  • Nplate® is given as a subcutaneous (SC) injection under the skin one time each week. You may not give Nplate® injections to yourself.
  • Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to have blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
  • Tell your healthcare provider about any bruising or bleeding that occurs while you are receiving Nplate®.
  • If you miss a scheduled dose of Nplate®, call your healthcare provider to arrange for your next dose as soon as possible.

Getting to your right dose1

  • The initial recommended dose for Nplate® is based on your actual body weight.
  • Your doctor will adjust your weekly dose until you reach a platelet count range that reduces the risk of bleeding.
  • Don't get discouraged if you don’t reach your treatment goal right away. It takes some patients several weeks and may require dose adjustments* until a stable platelet count is reached.
  • Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to have blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
  • Work with your doctor and stay with your treatment plan.

*In clinical trials, the average number of dose changes until patients reached a platelet count high enough to reduce the risk for bleeding was 3. Not all patients were able to reach a platelet count above 50,000 per microliter.1,2

The information you receive from the Nplate® Navigator is not meant to replace the advice of your healthcare team. Amgen will not provide medical advice regarding your medical condition. The Nplate® Navigator is not intended to diagnose health problems or to take the place of talking with your doctor about your condition, treatment, or medication. Be sure to talk to your doctor at your next visit if you have any questions about adult chronic ITP or Nplate®.

Checking your platelet count regularly1

  • Your doctor will check your platelet count every week at first.
  • Your doctor will change your Nplate® dose as needed until you achieve a platelet count high enough to reduce the risk for bleeding for 4 weeks in a row. After that, blood tests will be taken every month.
  • If you stop taking Nplate®, blood tests are needed for at least 2 weeks after. This is to check if your platelet count drops too low.
  • Tell your healthcare provider about any bruising or bleeding that occurs while you are receiving Nplate®.
  • If you miss a scheduled dose of Nplate, call your healthcare provider to arrange for your next dose as soon as possible.
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