INDICATIONS

Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:

  • adults with immune thrombocytopenia (ITP) when certain medicines or surgery to remove your spleen have not worked well enough. Read More
  • children 1 year of age and older with ITP for at least 6 months when certain medicines or surgery to remove your spleen have not worked well enough.

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HELPFUL RESOURCES
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Are you looking for more information and support for immune thrombocytopenia (ITP) and Nplate®? The videos, resources, groups, and programs on this page can help.

VIDEOS & DOWNLOADS

  • Videos

  • Downloads

Watch these stories of people living with ITP, how they spoke up to their doctors, and how Nplate® can help.

Lib’s story

Hear Lib’s story about being on steroids, having a splenectomy, and then Nplate® treatment.

ally takes control

Ally is worried her current medication isn’t working. She’s ready to talk about her goals and other treatment options.

TOMMY SPEAKS UP

Tommy tells his doctor about concerns with his current treatment. They talk about his options.

Maura Makes a Game Plan

It takes teamworkbut Maura, her mom, and her doctor come up with a game plan for her ITP treatment.

See How Nplate® Works

Nplate® helps the body to make more platelets, which can help reduce the risk of bleeding in people with ITP.

The Story of Nplate®

For more than 13 years, Nplate® has been helping people who have ITP.

ITP community

Platelet Disorder Support
Association (PDSA)

A nonprofit organization dedicated
to enhancing the lives of people with
ITP and other platelet disorders
through education, advocacy,
research, and support.

pdsa.org

ITP Support Association

A UK-registered charity that aims to
promote and improve the general
welfare of people with ITP.

itpsupport.org.uk

National Heart, Lung, and
Blood Institute

A globally led institute that supports
and conducts heart, lung, and blood
disease research on behalf of the
federal government at the National
Institutes of Health (NIH).

nhlbi.nih.gov

American Society of
Hematology

The world’s largest professional
society working to conquer blood
diseases.

hematology.org

Platelets on the Web

Useful information for physicians,
patients, and caregivers about
immune thrombocytopenia (ITP).

ouhsc.edu/platelets

These third-party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources. When using these websites and resources, look over the information carefully so you can understand how it applies to your needs. Always talk to your doctor about any questions regarding your ITP treatment.

NPLATE® SUPPORT & RESOURCES

Did you know icon

Nplate® has the highest % of patient claims (73%) with $0 out-of-pocket costs vs oral ITP medications (56%)*

*Analysis from 2021 to 2022 for Commercial and Medicare patient claims combined. Data based on IQVIA LAAD claims data. Oral OOP percent is a weighted average of claims for eltrombopag, avatrombopag, and fostamatinib disodium hexahydrate.

Amgen® SupportPlus logo

We’re right here, right when you need us

With financial support resources and other helpful patient support services, we are here to help you along the way.

Call Amgen® SupportPlus at 866-264-2778  
Monday - Friday 9:00 AM to 8:00 PM ET.

Visit AmgenSupportPlus.com to learn how Amgen can help.

Financial support icon

Financial Support

Amgen® Support Plus card

Amgen® SupportPlus logo

If you have private or commercial insurance that you get from your employer or buy directly from a health insurance company, you may be eligible to pay as little as $0* for your prescription.

The Amgen SupportPlus Co-Pay Program may help patients with private or commercial insurance lower their out-of-pocket costs

  • Pay as little as $0* out-of-pocket for each dose or cycle
  • Can be applied to deductible, co-insurance, and co-payment*
  • No income eligibility requirement

Check your eligibility and sign up today at www.AmgenSupportPlus.com/copay

*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay for full Terms and Conditions.

What if I don’t have private or commercial insurance (eg, self-purchased or through an employer)?

Amgen® SupportPlus can provide information about independent nonprofit foundations that may be able to help.
Call Amgen® SupportPlus at 866-264-2778 Monday - Friday 9:00 AM – 8:00 PM ET to learn more.

Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofit’s criteria. Amgen has no control over these programs and provides information as a courtesy only.

Amgen® Nurse Partner icon

Amgen® Nurse Partners

Dedicated Amgen Nurse Partners can offer supplemental support to help you on your treatment journey, including:

  • Guidance on resources that may help lower out-of-pocket medication costs
  • Assistance to help you stay on track with your medication
  • Answers to your questions about Amgen SupportPlus

Get connected with a dedicated Amgen Nurse Partner by enrolling in Amgen SupportPlus:

  • Download and complete the Amgen SupportPlus Enrollment Form found on AmgenSupportPlus.com and give it to your doctor to complete and fax to 866-218-4777
  • Call 866-264-2778 to enroll by phone

Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.

Did you know icon

A majority of people pay nothing for Nplate®*

*In an analysis of 25,923 Nplate® claims identified between 1/1/2020 - 12/31/2020, 74% had a $0 out-of-pocket (OOP) cost. This included all payers, including commercial and government plans. Among the 26% of Nplate® claims where patients had OOP costs, most claims (70%) had an OOP cost of less than $500. Data based on IQVIA LAAD claims data.

For information on any of these programs, connect with us at

Monday through Friday - 9:00 AM to 8:00 PM ET

Frequently Asked Questions about Nplate® (romiplostim)

What is Nplate®?

Nplate® is a treatment for low platelet counts in adults and children with immune thrombocytopenia (ITP) when other treatments or medicines have not worked well enough.

LEARN MORE ABOUT HOW NPLATE® CAN HELP

How could Nplate® help adults with ITP?

  • Once-weekly Nplate® has been proven to boost and sustain platelets to lower the risk of bleeding
  • In a study, the majority of adults were able to keep their platelet counts above 50,000 for at least 11 out of the 12 months they were studied
  • Some of these people were able to stop their ITP treatment with Nplate® and still keep their platelet counts up, called treatment-free remission

    learn more about platelet stability and remission with Nplate®

How could Nplate® help children with ITP?

Studies have shown that 7 out of 10 children (n=30/42) treated with Nplate® were able to raise their platelet levels to 50,000 or higher.

Learn more about Nplate® for children

What can I expect with Nplate®?

Nplate® is a shot (injection) given by your doctor or nurse once a week. Nplate® has no dietary restrictions and no known drug interactions. This means you won't have to change your meal schedule or other medicines.

LEARN MORE ABOUT TAKING Nplate®

What is the most important information I should know about Nplate®?

Nplate® can cause serious side effects, including:

  • Worsening of a precancerous blood condition to a blood cancer (leukemia). Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
  • Higher risk for blood clots.
    • You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.
    • If you have a chronic liver disease, you may get blood clots in the veins of your liver. This may affect your liver function.
  • Injection of too much Nplate® may cause a dangerous increase in your blood platelet count and serious side effects.
    Your healthcare provider may change your dose or stop Nplate® depending upon the change in your blood platelet count. You must have blood platelet counts done before you start, during, and after Nplate® therapy is stopped.

See What are the possible side effects of Nplate®? for other side effects of Nplate®.



What are the possible side effects of Nplate®?

Nplate® can cause serious side effects.

The most common side effects of Nplate® in adults include:

  • headache
  • joint pain
  • dizziness
  • trouble sleeping
  • muscle tenderness or weakness
  • pain in the arms and legs
  • stomach (abdomen) pain
  • shoulder pain
  • indigestion
  • tingling or numbness in hands and feet
  • bronchitis
  • inflammation of the sinuses (sinusitis)
  • vomiting
  • diarrhea
  • upper respiratory tract infection
  • cough
  • nausea
  • pain in mouth and throat (oropharyngeal pain)
Learn about how Nplate® works for adults

The most common side effects of Nplate® in children 1 year of age and older include:

  • bruising
  • upper respiratory tract infection
  • pain in mouth and throat (oropharyngeal pain)
Learn about how Nplate® works for children

How do I get my Nplate® shot when I'm out of town?

When you're away from your regular doctor or nurse who gives you your Nplate® shot, the ITP Specialist Finder can help you locate a healthcare professional that can administer Nplate®.

learn more

Is there information on long-term safety for Nplate®?

The long-term safety data for Nplate® illustrated that side effects did not increase in frequency with longer drug exposure. The study looked at some patients from previous Nplate® studies. Other safety data can be found in the Prescribing Information and the Important Safety Information.

Learn about how Nplate® was studied in adults

CAN I GET HELP PAYING FOR THE COST OF NPLATE®?

We know every patient has unique needs. And we’re here to provide financial support information and resources, regardless of your current financial situation or type of insurance you have. Visit AmgenSupportPlus.com to learn more.

What support is available for people taking Nplate®?

Dedicated Amgen Nurse Partners* will be with you along the way to offer supplemental support and provide information about resources to help you access your prescribed Amgen medication.

*Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.


Call 866-264-2778 to enroll by phone

DON'T SEE YOUR QUESTION HERE? ASK YOUR HEALTHCARE TEAM

Important Safety Information

What is the most important information I should know about Nplate®?

  • Nplate® can cause serious side effects, including:
  • Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.

  • Higher risk for blood clots:

    • You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.
    • If you have a chronic liver disease, you may get blood clots in the veins of your liver. This may affect your liver function.
  • What are the possible side effects of Nplate®?

    • Nplate® may cause serious side effects. See “What is the most important information I should know about Nplate®?”
    • The most common side effects of Nplate® in adults include:
      • headache
      • joint pain
      • dizziness
      • trouble sleeping
      • muscle tenderness or weakness
      • pain in arms and legs
      • stomach (abdomen) pain
      • shoulder pain
      • indigestion
      • tingling or numbness in hands and feet
      • bronchitis
      • inflammation of the sinuses (sinusitis)
      • vomiting
      • diarrhea
      • upper respiratory tract infection
      • cough
      • nausea
      • pain in mouth and throat (oropharyngeal pain)
    • The most common side effects of Nplate® in children 1 year of age and older include:
      • bruising
      • upper respiratory tract infection
      • pain in mouth and throat (oropharyngeal pain)
      • headache
    • People who take Nplate® may have an increased risk of developing new or worsening changes in the bone marrow called “increased reticulin.” These changes may improve if you stop taking Nplate®. Your healthcare provider may need to check your bone marrow for this problem during treatment with Nplate®.
    • These are not all the possible side effects of Nplate®. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.
    • If you have any questions about this information, be sure to discuss with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How will I receive Nplate®?

Nplate® is given as an injection under the skin (subcutaneous) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.

APPROVED USES

Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:

  • adults with immune thrombocytopenia (ITP) when certain medicines or surgery to remove your spleen have not worked well enough.
  • children 1 year of age and older with ITP for at least 6 months when certain medicines or surgery to remove your spleen have not worked well enough.

Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS), or low platelet count caused by any condition other than immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.

Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.

References

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Important Safety Information

What is the most important information I should know about Nplate®?

  • Nplate® can cause serious side effects, including:
  • Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.

  • Higher risk for blood clots:

    • You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.