Platelets help your blood to clot, which helps to stop bleeding.
Platelet destruction in ITP causes your normal platelet count to drop below what it should be. Depending on how
low your platelet count is, bruising and bleeding may occur.
Nplate® has been proven to boost and sustain platelets to lower the risk of bleeding.
If a person with ITP has very low platelet counts, it is possible to have internal bleeding or, in rare cases, bleeding in the brain. Severe bleeding is rare in ITP.
It’s important to tell your doctor about any symptoms you are experiencing and your complete medical history.
As you manage your ITP with your doctor, it may help to set a goal for your platelet counts that can be sustained over time. Platelet counts can rise and fall even if your treatment is working, so your healthcare team will try to keep your count within a certain range rather than at an exact number. Talk to your doctor about what's right for you.
You may have experienced mixed results or side effects from other treatments. ln fact, living with ITP can sometimes feel like a roller coaster. If you’ve felt disappointed with your treatments so far, you may be looking for more stability.
Once-weekly Nplate® could help.
Platelets are made by cells in the bone marrow. The amount of platelets your body makes is controlled by a protein called thrombopoietin (TPO). In people with ITP, the amount of TPO is not high enough to keep platelet production up sufficiently to overcome the platelet destruction.
Nplate® works like TPO, telling the bone marrow to make more platelets, which can help reduce the
risk of bleeding in people with ITP.
Important Safety Information
What is the most important information I should know about Nplate®?
Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
Higher risk for blood clots:
What are the possible side effects of Nplate®?
How will I receive Nplate®?
Nplate® is given as an injection under the skin (subcutaneous) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:
Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS), or low platelet count caused by any condition other than immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.
Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.