Nplate® is a treatment for low blood platelet counts in adults with chronic immune thrombocytopenia (ITP). Nplate® is used when certain other medicines, or surgery to remove the spleen, have not worked well enough.
*Based on overall platelet response.
Nplate® is an injection given by your doctor or nurse once a week. Nplate® has no dietary restrictions and no known drug interactions. This means you won't have to change your meal schedule or other medicines.
Nplate® can cause serious side effects, including:
Your healthcare provider will closely monitor your Nplate® dose and blood tests, including platelet counts during treatment.
See “What are the possible side effects of Nplate®?” for other side effects of Nplate®.
Nplate® may cause serious side effects.
The most common side effects of Nplate® are:
The long-term safety data for Nplate® illustrated that adverse events did not increase in frequency with longer drug exposure. The study looked at some patients from previous Nplate® studies. Other safety data can be found in the Prescribing Information and the Important Safety Information.
Whatever type of insurance you have–even if you have none–Nplate® Navigator can help you understand how your Nplate® medicine may be covered, and refer you to programs that may be able to help you afford it, such as Nplate® Amgen FIRST STEP™.
If you’ve been prescribed Nplate®, you might have questions about your medicine, how it may be covered by your insurance, or resources within your community. That’s why we created Nplate® Navigator—so you have a single place to go to find the support, tools, and resources* most important to you.
*Resources include referrals to independent nonprofit patient assistance programs. Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofits’ criteria. Amgen has no control over these programs and provides referrals as a courtesy only.
Important Safety Information
What is the most important information I should know about Nplate®?
Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
Higher risk for blood clots:
What are the possible side effects of Nplate®?
How will I receive Nplate®?
Nplate® is given as an injection under the skin (subcutaneous) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:
Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS), or low platelet count caused by any condition other than immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.
Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.