INDICATIONS

Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:

  • adults with immune thrombocytopenia (ITP) when certain medicines or surgery to remove your spleen have not worked well enough. Read More
  • children 1 year of age and older with ITP for at least 6 months when certain medicines or surgery to remove your spleen have not worked well enough.

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PATIENT RESOURCES

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Whether you're looking for co-pay support, ITP community resources, or just want to learn more about Nplate® (romiplostim) and ITP, we've got it all here.

NPLATE® SUPPORT

Nplate® support from every angle

If you’ve been prescribed Nplate®, you might have questions about your medicine, how it may be covered by your insurance, or resources within your community. That’s why we created Nplate® Navigator—so you have a single place to go to find the support, tools, and resources* most important to you.

Amgen Nurse Navigators

  • Referrals to financial support options for any insurance type
  • Answers to medication questions
  • Resources for day-to-day living*
Call 1-888-4ASSIST (1-888-427-7478) to speak to an Amgen Nurse Navigator, Monday through Friday, 9 AM to 8 PM ET or SIGN UP HERE

*Resources include referrals to independent nonprofit patient assistance programs. Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofits’ criteria. Amgen has no control over these programs and provides referrals as a courtesy only.

Amgen Nurse Navigators are only available to patients that are prescribed certain products. Nurse Navigators are there to support, not replace, your treatment plan and do not provide medical advice or case management services. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.

FINANCIAL ASSISTANCE

Whatever type of insurance you have—even if you have none—Amgen Nurse Navigator can help you understand how your Nplate® medicine may be covered, and refer you to programs that may be able to help you afford it, such as Amgen FIRST STEP™. See below for more information.

Amgen FIRST STEP™

For eligible§ commercially insured patients

If you are an eligible commercially insured patient, Amgen FIRST STEP™ can help cover your out-of-pocket prescription costs, including deductible, co-insurance, and co-payment.

  • $0 out-of-pocket for first dose or cycle
  • $5 out-of-pocket for subsequent doses or cycles, up to the brand program benefit maximum
  • No income eligibility requirement

Visit Amgen FIRST STEP™ now

Provided through independent nonprofit patient assistance programs, program eligibility is based on the nonprofit's criteria. Amgen has no control over these programs and provides referrals as a courtesy only.

§Terms, conditions, and program maximums apply. This program is not open to patients receiving prescription reimbursement under any federal, state, or government-funded healthcare program. Not valid where prohibited by law.

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81% of Nplate® claims have $0 out-of-pocket costs for the patient

Among the 19% of Nplate® claims where patients had OOP costs, most claims (72%) had an OOP cost of less than $400. Data based on Symphony Health Solutions claims data. 24,199 Nplate® claims were identified between 1/1/2019-12/31/2019 for all payors, including commercial and government.

For more information, call Amgen Nurse Navigator or call Amgen FIRST STEP™ Program directly.
1-888-65-STEP1 (1-888-657-8371), Monday - Friday, 9 AM - 8 PM ET or visit amgenfirststep.com

Helpful resources

Download these tools to help you get started on Nplate® and track your platelet counts

Videos and downloadable tools about ITP, treatment, and talking to your healthcare team

The Story of Nplate®

Nplate® for ITP: 10 years and counting

See How Nplate® Works

Nplate® helps the body to make more platelets which can help reduce the risk of bleeding in people with ITP

Patient Stories

Hear Lib’s story about being on steroids, having a splenectomy, and then Nplate® treatment

Maura Makes a Game Plan

It takes teamworkbut Maura, her mom, and her doctor come up with a game plan for her ITP treatment

Tommy Gets Candid

Tommy tells his doctor about concerns with his current treatment. They talk about his options

Ally Is Frustrated

Ally’s worried her current medication isn’t working. She’s ready to talk about her goals and other treatment options

ITP community websites for groups and organizations

Platelet Disorder Support
Association (PDSA)

A nonprofit organization dedicated
to enhancing the lives of people with
ITP and other platelet disorders
through education, advocacy,
research, and support.

pdsa.org

ITP Support Association

A UK-registered charity that aims to
promote and improve the general
welfare of people with ITP.

itpsupport.org.uk

National Heart, Lung, and
Blood Institute

A globally led institute that supports
and conducts heart, lung, and blood
disease research on behalf of the
federal government at the National
Institutes of Health (NIH).

nhlbi.nih.gov

American Society of
Hematology

The world’s largest professional
society working to conquer blood
diseases.

hematology.org

Platelets on the Web

Useful information for physicians,
patients, and caregivers about
idiopathic thrombocytopenic
purpura (ITP).

ouhsc.edu/platelets

These third-party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources. When using these websites and resources, look over the information carefully so you can understand how it applies to your needs. Always talk to your doctor about any questions regarding your ITP treatment.

SIGN UP FOR NPLATE® NAVIGATOR

Important Safety Information

What is the most important information I should know about Nplate®?

  • Nplate® can cause serious side effects, including:
  • Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.

  • Higher risk for blood clots:

    • You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.
    • If you have a chronic liver disease, you may get blood clots in the veins of your liver. This may affect your liver function.
  • What are the possible side effects of Nplate®?

    • Nplate® may cause serious side effects. See “What is the most important information I should know about Nplate®?”
    • The most common side effects of Nplate® in adults include:
      • headache
      • joint pain
      • dizziness
      • trouble sleeping
      • muscle tenderness or weakness
      • pain in arms and legs
      • stomach (abdomen) pain
      • shoulder pain
      • indigestion
      • tingling or numbness in hands and feet
      • bronchitis
      • inflammation of the sinuses (sinusitis)
      • vomiting
      • diarrhea
      • upper respiratory tract infection
      • cough
      • nausea
      • pain in mouth and throat (oropharyngeal pain)
    • The most common side effects of Nplate® in children 1 year of age and older include:
      • bruising
      • upper respiratory tract infection
      • pain in mouth and throat (oropharyngeal pain)
      • headache
    • People who take Nplate® may have an increased risk of developing new or worsening changes in the bone marrow called “increased reticulin.” These changes may improve if you stop taking Nplate®. Your healthcare provider may need to check your bone marrow for this problem during treatment with Nplate®.
    • These are not all the possible side effects of Nplate®. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.
    • If you have any questions about this information, be sure to discuss with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How will I receive Nplate®?

Nplate® is given as an injection under the skin (subcutaneous) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.

APPROVED USES

Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:

  • adults with immune thrombocytopenia (ITP) when certain medicines or surgery to remove your spleen have not worked well enough.
  • children 1 year of age and older with ITP for at least 6 months when certain medicines or surgery to remove your spleen have not worked well enough.

Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS), or low platelet count caused by any condition other than immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.

Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.

References

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Important Safety Information

What is the most important information I should know about Nplate®?

  • Nplate® can cause serious side effects, including:
  • Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.

  • Higher risk for blood clots:

    • You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.