Support and resources
Support from every angle
Chronic ITP can feel overwhelming. We understand.
If you’ve been prescribed Nplate®, you might have questions about yourSign up for Nplate® Navigator
medicine, how it may be covered by your insurance, or resources within your
community. That’s why we created Nplate® Navigator—so you have a single
place to go to find the support, tools, and resources* most important to you.
Call toll-free: 1-855-7Nplate
Monday - Friday, 9AM - 8PM EST
Co-pay and reimbursement resources*
Whatever type of insurance you have—even if you have none— Nplate® Navigator can help you understand how your
Nplate® medicine may be covered, and refer you to programs that may be able to help you afford it, such as Amgen FIRST STEP™. See below for more information.
*Resources include referrals to independent nonprofit patient assistance programs. Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofits’ criteria. Amgen has no control over these programs and provides referrals as a courtesy only.
Your Nplate® Navigator Nurse Ambassador† may help you find answers to questions about Nplate®.
Find an ITP specialist
If you are planning to travel or relocate, the
ITP Specialist Finder
can help you locate a doctor who may be able to administer your weekly Nplate® treatment. And if you prefer,
you can also call
Nplate® Navigator to get help finding an ITP specialist near your location.
†Nplate® Navigator Nurse Ambassadors are only available to patients that are prescribed certain products. Nurses are there to support, not replace, your treatment plan and do not provide medical advice or case management services. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.
Learn about a co-pay program
Amgen FIRST STEP™ Program
The Amgen FIRST STEP™ program can help eligible‡ commercially insured patients cover their out-of-pocket prescription costs, including deductible, co-insurance, and co-payment.
For more information, call Nplate® Navigator or call Amgen FIRST STEP™ Program directly.
‡Terms, conditions, and program maximums apply. This program is not open to patients receiving prescription reimbursement under any federal, state, or government-funded healthcare program. Not valid where prohibited by law.
ITP community websites
Below you'll find a few helpful support groups and national organizations that provide information about ITP and patient support. When using any of these resources, look over the information you receive carefully so that you can understand how it may apply to your specific support needs. Always consult your doctor if you have specific questions about your ITP treatment.
Platelet Disorder Support Association (PDSA)
A nonprofit organization dedicated
to enhancing the lives of people
with ITP and other platelet
disorders through education,
advocacy, research, and support.
Health Monitor Guide
An ITP-focused partner site of
Health Monitor, a leading online
destination for those seeking
trusted, user-friendly information
about various health-related topics.
A UK-registered charity that aims to promote and improve the general welfare of people with ITP.itpsupport.org.uk
National Heart, Lung, and
A globally led institute that supports and conducts heart, lung, and
blood disease research on behalf
of the federal government at the
National Institutes of Health (NIH).
American Society of
The world’s largest professional
society working to conquer blood
Useful information for physicians, patients, and caregivers about idiopathic thrombocytopenic
These third-party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources.
Downloadable education and resources
You can download and use these Nplate® resources to answer questions about your ITP, record your medical history and symptoms, and guide your discussion with your healthcare team.
Summary of Symptoms
and Medical History
Helps you keep your symptoms
and medical history in one
convenient place to share with your
Doctor Discussion Guide
Can help direct your discussion
about Nplate® with your healthcare
Nplate® Dose and
Track the changes to your platelet
counts and your dose each week
Nplate® Patient Brochure
Can help you understand ITP and
how Nplate® could help
Nplate® Pediatric Patient &
Learn about ITP in children and
how Nplate® could help
Call Nplate® navigator to talk to a registered nurse
Important Safety Information
What is the most important information I should know about Nplate®?
- Nplate® can cause serious side effects, including:
Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS) or for any condition other than chronic (lasting a long time) immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
Higher risk for blood clots:
- You may have a higher risk of getting a blood clot if your platelet count becomes high during treatment with Nplate®. You may have severe complications or die from some forms of blood clots, such as clots that spread to the lungs or that cause heart attacks or strokes.
- If you have a chronic liver disease, you may get blood clots in the veins of your liver. This may affect your liver function.
What are the possible side effects of Nplate®?
- Nplate® may cause serious side effects. See “What is the most important information I should know about Nplate®?”
- The most common side effects of Nplate® in adults include:
- joint pain
- trouble sleeping
- muscle tenderness or weakness
- pain in arms and legs
- stomach (abdomen) pain
- shoulder pain
- tingling or numbness in hands and feet
- The most common side effects of Nplate® in children 1 year of age and older include:
- inflammation of the passages in the nose and throat
- upper respiratory tract infection
- itchy, runny, or blocked nose
- sore throat and discomfort with swallowing
- inflammation of the eye
- ear infection
- inflammation in the lining of the intestines
- inflammation of the sinuses
- pain in mouth and throat
- upper stomach (abdomen) pain
- bleeding beneath the surface of the skin or bruising under the skin
- itchy rash
- swelling in the limbs/hands/feet
- People who take Nplate® may have an increased risk of developing new or worsening changes in the bone marrow called “increased reticulin.” These changes may improve if you stop taking Nplate®. Your healthcare provider may need to check your bone marrow for this problem during treatment with Nplate®.
- These are not all the possible side effects of Nplate®. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.
- If you have any questions about this information, be sure to discuss with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
How will I receive Nplate®?
Nplate® is given under the skin (subcutaneous injection) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
Pregnancy Surveillance Program: Women who become pregnant during Nplate® treatment are encouraged to enroll in Amgen’s Pregnancy Surveillance Program. The purpose of this program is to collect safety information about the health of you and your baby. Contact the program as soon as you become aware of the pregnancy, or ask your healthcare provider to contact the program for you. You or your healthcare provider can get information and enroll in the program by calling 1-800-77-AMGEN (1-800-772-6436).
Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:
- adults with chronic immune thrombocytopenia (ITP) when certain medicines or surgery to remove your spleen have not worked well enough.
- children 1 year of age and older with ITP for at least 6 months when certain medicines or surgery to remove the spleen have not worked well enough.
Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS) or low platelet count caused by any condition other than chronic (lasting a long time) immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.
Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.