Managing Your Platelet Count

Setting treatment goals for adult chronic ITP

Generally, the most important goal in treating chronic ITP is to reach a platelet count that will reduce the risk of bleeding. Another goal may be to relieve the symptoms of chronic ITP, such as bruising and other bleeding symptoms that may be severe.1

To reduce the risk of bleeding, your doctor may try to:
  • Raise your platelet count to at least 50,000 per microliter and maintain that level in order to help reduce the risk of bruising and other bleeding symptoms. These symptoms most often occur at platelet counts less than 50,000 per microliter.1
  • Keep your platelet count within a certain range, rather than an exact number.1-3 Even when you are on therapy that works for you, platelet counts can rise and fall from week to week.4

ITP is different for everyone, so don’t get discouraged if you don’t reach your treatment goal right away.1 It is important to stay with your treatment plan and visit your doctor regularly. Although there is no cure for adult chronic ITP, you can work closely with your doctor to help manage your condition.

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Defining your platelet range

A normal platelet count ranges from 150,000 to 450,000 per microliter of blood.4 Although patients can be diagnosed with ITP when their platelets fall below 100,000 per microliter of blood, ITP symptoms such as increased bruising are more likely to occur in patients with platelet counts between 30,000-50,000 per microliter. Severe internal and external bleeding is most often seen in patients with platelet counts below 10,000 per microliter of blood.5 The goal of most ITP treatments is to maintain a platelet count above 50,000 per microliter.1

Platelet Count Ranges

Platelet count per microliter of blood

450,000
400,000
350,000
300,000
250,000
200,000
150,000
100,000
50,000
10,000 or less

A platelet count goal in chronic ITP: ≥ 50,0002
The risk of bruising and bleeding increases with decreased platelet counts.1,5

Tracking platelet counts and symptoms

Tracking your platelet counts and symptoms is an important way to monitor whether you are meeting your ITP treatment goals. Your doctor will use a blood test to regularly check if your platelet count is within a range sufficient to reduce the risk of bleeding. Talk to your doctor and you can use this Nplate® Dose and Platelet Tracker to keep a record of your platelet counts, doctor visits, and other important ITP treatment plan details.

You should also tell your doctor about any symptoms at each visit. This information may help your doctor tell whether or not your ITP treatment is working. Talk to your doctor and use this summary to keep track of any new symptoms or changes in your health or medical history and you may want to bring it each time you visit your doctor, so that he can adjust your dose appropriately.

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